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The Cancer Kickers Big Buffalo 50

50 Mile, 50K, 50K Relay + 10K Race

THE CANCER KICKERS BIG BUFFALO 50
March 21, 2026
Shelby Farms Park

The Cancer Kickers Big Buffalo 50 is more than a race. It’s a lifeline.

As the largest annual fundraiser for the Cancer Kickers Soccer Club, every stride taken on race day directly fuels hope, joy, and connection for children around the world who are fighting cancer.

Founded in Memphis in 2016 by Michelle and Chris Clothier, CKSC is a 501(c)(3) nonprofit dedicated to wrapping kids in comfort and community during the hardest battle of their lives. Through custom soccer kits, complete with jerseys, balls, gear, and personalized touches, we remind each child that they’re not facing cancer alone. So far, more than 3,200 kids have received their own kit of courage.

This year, we’re calling on the Memphis running community to help us reach even more children. During registration, you’ll have the option to make a donation to CKSC and every single dollar goes straight to the mission.

It costs $300 to deliver one complete kit to a child. That means:

  • Every relay team registered supports one child.
  • Every four 50K runners support one child.
  • Every three 50-mile runners support one child.

Your gift, no matter the size, has the power to brighten a child’s day, lift a family’s spirits, and remind them they’re part of a team that cares. Together, we can create real, meaningful impact for these brave kids.

Let’s run with purpose. Let’s run for them.

Watch our special video to see how Cancer Kickers transforms lives and hear firsthand from an incredible family whose world was changed by our team.


Register prior to January 31st and have your swag mailed directly to you in advance!

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Course Map

50 MILE (8 LAPS) - 50K & RELAY (5 LAPS) - 10K (1 LAP)

The 50 mile course will close 12 hours after the start of the race which will be 6pm in the evening. The 50k course cut off is 10 hours or 6pm and the Relay is 8 hours or 6pm.

The 2026 Big Buffalo Course will run the Natural direction of the Tour de Wolf Trail. This will increase the number of trail markers as we are able to use 95% of the permanent markers for the tour de wolf trail that are already in place.

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The 50 mile course will close 12 hours after the start of the race which will be 6pm in the evening. The 50K course cut off is 10 hours or 6pm and the Relay is 8 hours or 6pm.

Aid Stations

There are 3 aid stations on course. Each aid station will provide water & Hammer Nutrition Heed Electrolyte Drink. We will have: GU’s (both rocktane and regular) & Hammer gels; lays; PB&J’s; oranges; bananas; Oreos; granola bars; snickers; and gummies.

Relay Details

  • Relay Starts @ 10am
  • Relay Team packets will be picked up for the ENTIRE Team when the first team members picks up the packet. All Bibs, Shirts, and your Ankle Timing Chip are in the packet.
  • The Relay exchange is located just beyond the Start/Finish/Split Line.
  • Relay runners will only exchange an ankle chip as part of the relay.
  • Teams with less than 5 runners will mean that someone on the team will have to run multiple loops. There is no additional exchange for teams of less than 5 members.
  • Teams are encouraged to bring tents, coolers, chairs, and tailgate gear to make themselves at home while others are running. Tents can be setup starting at Noon on Friday and are listed in the blue section on the map below.

Contact information

Event contact
Start 2 Finish Event Management
Phone
901-274-2202